Clinical Trials

Genetic Immunity's DermaVir Patch is a potential first-in-class antiviral nanomedicine designed to inhibit viral replication by cytotoxic killing of HIV-infected cells. Currently, there are no approved immune magnifying nanomedicinces on the market to treat HIV/AIDS. The following DermaVir trials were started:

Phase I (GIHU004)

A PHASE I STUDY TO EVALUATE THE TOLERABILITY AND SAFETY OF A LC002, A DERMAVIR VACCINE, IN HIV-1-INFECTED SUBJECTS CURRENTLY UNDER TREATMENT WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)

Principal Investigator:
Denes Banhegyi, M.D.
St. Laszlo Hospital
Budapest
Hungary

To read Study Synopsis click here...

Phase I/II (ACTG 5176)

A PHASE I/II, RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF LC002, A DERMAVIR VACCINE, IN HIV-1-INFECTED SUBJECTS CURRENTLY UNDER TREATMENT WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)

Protocol Chair:
Richard Pollard, M.D.
University of California,
Davis Medical Center

To read Study Synopsis click here...

Phase II (DermHIVImm)

ACTIVE IMMUNOTHERAPY AGAINST HIV DURING HIGHLY ACTIVE ANTI-RETROVIRAL THERAPY FOLLOWED BY REPEATED TREATMENT INTERRUPTIONS, VAC 09. A PHASE I

Principal Investigator:
Professor Eric Sandstrom, M.D.
Karolinska University Hospital
Stockholm
Sweden

To read Study Synopsis click here...

Phase II (GIEU006)

PHASE II, RANDOMIZED, PLACEBO-CONTROLLED, MULTI-CENTER STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND ANTIRETROVIRAL ACTIVITY OF DERMAVIR (LC002) PATCH IN TREATMENT-NAĎVE HIV-1-INFECTED PATIENTS

Principal Investigator:
Jan. van Lunzen, M.D., Ph.D.
University Medical Center
Hamburg Eppendorf
Germany

To read Study Synopsis click here...

Phase I/II IMPAACT-P1049 (in preparation)

A PHASE I/II STUDY OF THE SAFETY, TOLERABILITY AND IMMUNOGENECITY OF A TOPICAL THERAPEUTIC DNA DENRITIC CELL VACCINE (DERMAVIR PATCH) IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS WITH HIV-1 INFECTION ON HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART).

Protocol Chair:
Hans Spiegel, M.D.
Assistant Professor of Pediatrics, Microbiology & Tropical Medicine
The George Washington University Children's National Medical Center